On 25 November 2011, Alkarama and Human Rights Guardians sent a communication to the United Nations Working Group on Enforced or Involuntary Disappearances (WGEID) regarding the case of 49-year-old retired policeman Khalid Zain, his 29-year-old son Mohammad Zain and another family member, 30-year-old Abdallah Zain. They all disappeared after their respective arrests between July 2011 and August 2012.
On 16 November 2015, Alkarama and Human Rights Guardians sent a communication to the UN Working Group on Enforced Disappearances (WGEID) regarding the case of 47-year-old Mohamad Hallak, who disappeared after his arrest by members of the Syrian Military Security Branch at a checkpoint close to the border with Lebanon in November 2014.
On 12 November 2015, Alkarama and Human Rights Guardians sent a communication to the United Nations Working Group on Enforced or Involuntary Disappearances (WGEID) regarding the case of 34-year-old medication distributor Mansour Mansour, who disappeared after arrest by members of the Syrian Army and Syrian Security Services in July 2012.
On 29 October 2015 Alkarama and Human Rights Guardians sent a communication to the United Nations Working Group on Enforced or Involuntary Disappearances (WGEID) regarding the case of Ahmad Shamma, a 33-year-old self-employed professional who disappeared from Homs after his arrest by members of the Syrian army, the Military Intelligence Division and other members of the security forces.
On 14 October 2015, Alkarama and Human Rights Guardians sent a communication to the United Nations Commission of Inquiry on Syria on the enforced disappearance of Abdul Majid Al Satam, a 29-year-old member of the group Trustees of Raqqa – an armed group fighting both the Assad armed forces and the Islamic State (IS) − who disappeared after his abduction by IS in August 2013.