On 11 July 2016, Alkarama and Human Rights Guardians wrote to the United Nations Working Group on Enforced Disappearances (WGEID) regarding the cases of five Syrian citizens from the village of Kafr al-Tun who disappeared in the Governorate of Hama in western central Syria between 2012 and 2014. They were all arrested during raids and waves of arrest conducted by the Military Intelligence Directorate – or "Military Security" – or as they were passing checkpoints, after which they were brought to unknown places of detention. Their families did not take any action after their disappearance, fearing reprisals or to be arrested themselves.

Between February and March 2013, two brothers of the Al Arnaout family were arrested in Homs by the Military Security. More than three years later, their whereabouts remain unknown. Concerned over their fate, Alkarama submitted in June 2016 their case to the United Nations Working Group on Enforced Disappearances (WGEID), hoping its intervention will help shed light on their fate.

In recent years, checkpoints have become a tool for the Syrian authorities to create a climate of fear in the country. Individuals passing checkpoints are systematically thoroughly scrutinised by the security services and are, if perceived as supporting the opposition, arrested and brought to unknown places of detention, their families being denied any information on their fate and whereabouts.

On 25 March 2015, Walid Issa, a 27-year-old student from Al-Yaarubiyah in the al-Hasakah Governorate, was travelling home from Turkey when, passing in the city of Al Raqqah, he was stopped at Point 11, an area hosting the headquarters of the 'Islamic State' (IS) security offices near the soccer stadium known as "the black stadium." The officers, wearing black uniforms and identifying themselves as IS members, immediately arrested him.