On 27 January 2015, Alkarama sent an urgent appeal to the United Nations Special Rapporteur on Torture (SRT) regarding the case of Abdelrahman Mahmoud Omar Kamal, a 23-year-old civil engineer and charity worker arrested by the Homeland Security on 22 September 2014 and secretly detained and tortured for 119 days. He is still detained and at high risk of ill-treatment, while his family was only allowed to see him once.

Alkarama welcomes the release of Abdullah Abdulhallem Abdulhallem Zalat on 26 January 2015, for whom it had sent an urgent appeal to the United Nations Working Group on Enforced or Involuntary Disappearances (WGEID) asking for his release. Abdullah Zalat, a 31-year-old civil engineer had been abducted by the Egyptian Homeland Security forces after several members of the security forces had raided his house in the city of Tanta, 100km north of Cairo.

On 22 January 2015, Alkarama sent an urgent appeal to the United Nations Working Group on Enforced or Involuntary Disappearances (WGEID) regarding the case of Abdullah Abdulhallem Abdulhallem Zalat, a 31-year-old civil engineer abducted by the Egyptian Homeland Security forces on 16 January 2015 and has been missing since. Alkarama believes that he is at high risk of being subjected to ill-treatment whilst being secretly detained by the intelligence services.

Alkarama denounces the recent mass death sentences of 188 Egyptian citizens, including 53 in absentia, by the Gizeh criminal court in the trial regarding the 14 August 2013 attack on Kerdasa police station, a few hours after the massacres of Raba'a Al Adawiya and Al Nahda.

On 15 September 2014, Alkarama and Al Wissam Humanitarian Assembly sent a joint urgent appeal to the United Nations Committee on Enforced Disappearances concerning the abduction of Riad Abdel Majeed Al Obeidi, a former Air Force Brigade pilot, in Al A'amiriya on 1 June 2014. Having not been seen since, his family fears that he be tortured or ill-treated, particularly after he managed to contact them, from his detention place, in mid-June.

On 16 July 2014, the Secretary of the United Nations Working Group on Arbitrary Detention (WGAD), Miguel de la Lama informed Alkarama that, during its 69th session on 24 April 2014, the WGAD had recognised the arbitrary nature of the detention of 12 Egyptian citizens arrested in July and August 2013 during peaceful demonstrations, and consequently tried before military courts. The WGAD, which also considered that their right to freedom of expression had been breached, urged the Egyptian authorities to remedy to this situation by immediately releasing them and providing them with compensation.

On 14 July 2014, the police arrested 15 individuals during a violent dispersal of a peaceful demonstration in Al Fayoum. Detained in Badar Al Fayoum's police station since their arrest, they also report having been subjected to torture and ill-treatment.

On 27 August 2014, Alkarama referred the cases of 52 children subjected to torture and sexual abuses in Alexandria's Koum El Dekka prison to the UN Special Rapporteur on Torture. Aged between 15 and 18, they were arrested for demonstrating peacefully against the regime; most have now been detained arbitrarily for over eight months.

On 29 August 2014, Alkarama sent an urgent appeal to the United Nations Special Rapporteur on the Right to Health to ask the Egyptian authorities to accept Jamal Mohamed Assaed Tafeh's hospitalisation. Detained without trial in appalling conditions in Gamasa prison since 7 January 2014, the opposition member, who suffers from a serious heart disease that requires permanent medical attention, is at imminent risk of death.