On 26 January 2015, 21-year-old student Mohamed Faraj, who suffers from multiple sclerosis, was arrested from the courtroom after being sentenced by Bahrain's Fourth Criminal Court to seven years imprisonment for arson, illegal gathering and rioting. Mohamed was taken in his wheelchair to the Jaw prison, known for its "severe abuses" of prisoners, to serve his sentence. Concerned over his health, as he does not receive adequate medical treatment for his condition, Alkarama together with the Bahrain Forum for Human Rights sent on 12 February 2016 a communication to the United Nations Special Rapporteur on the right of everyone to the enjoyment of the highest attainable standard of physical and mental health (SR Health), Dainius Pūras, requesting him to call upon the Bahraini authorities to provide Mohamed with adequate treatment.

On 3 February 2016, 25-year-old photojournalist Ahmed Jaber Al Fardan was arrested, after being sentenced to three months imprisonment for allegedly attempting to attend an illegal gathering in 2013. Considering his detention arbitrary, on 5 February 2016, Alkarama sent an urgent appeal to the United Nations Working Group on Arbitrary Detention (WGAD), requesting it to call upon the Bahraini authorities to immediately release Al Fardan.

On 15 January 2016, Alkarama submitted a report to the Sub-Committee on Accreditation (SCA) of the International Coordinating Committee of National Institutions for the Promotion and Protection of Human Rights (ICC-NHRI) on Bahrain's National Institution for Human Rights (NIHR) which will be graded by the SCA between 9-13 May 2016. Pointing out its lack of independence from the executive power and lack of transparency, Alkarama called upon the SCA to grant Bahrain's NIHR status "B" to indicate its lack of compliance with the Paris Principles – the international standards established to ensure the NHRI's independence from government and effective promotion and protection of human rights. In its review of the Bahraini NHRI, the SCA will assess, among others, its pluralist representation of society, its independence from the government and the scope of its mandate.

On 2 December 2015, members of the Bahraini Security Forces arrested 21-year-old student Ali Abduljalil Mohamed Hassan and took him to the Criminal Investigation Directorate in Manama, where he has been detained incommunicado ever since. Concerned over these facts, on 22 December 2015, Alkarama sent an urgent appeal to the United Nations Working Group on Arbitrary Detention (WGAD), requesting itto urge the Bahraini authorities to release Ali immediately.