On 12 March 2010, Alkarama sent an urgent appeal to the Special Rapporteur on the situation of human rights, requesting her intervention with the Saudi authorities.

Prior to Thamer Bin Abdelkarim Al-Khodr's arrest, he and his father Dr. Abdelkarim Al-Khodr, Professor of Comparative Jurisprudence and founding member of the Association of Civil and Political Rights in Saudi Arabia, were verbally harassed for several days by agents of the local security services, are were most likely targeted due to their work as human rights activists.

Their relatives believe that Thamer Al-Khodr's arrest is in retaliation of his father's human rights activities and is intended to stop any further activism, either political or human rights related.

Thamer Al-Khodr and his father are both well-known human rights defenders in Saudi Arabia, having on several occasions called for the promulgation of the Saudi constitution and political reforms. On 8 March 2008, they published an appeal denouncing the inhumane conditions inside Al-Burayda prison, where prisoners of conscience and political detainees often remain without trial for several years; such as is the case with Dr. Abdullah Al-Hamed and his brother Aissa, both members of the Saudi Reform Movement and imprisoned since 8 March 2008.

Thamer Al-Khodr imprisonment is a calculated effort on the part of the Saudi authorities to silence political opponents and further deny human rights activists inside the Kingdom of their freedom of speech.