A 48-year-old lawyer and member of liberal political party Al Dostour, Raafat Faisal Ali Shehata − also known as Ahsraf Shehata − disappeared in the hands of the Egyptian Homeland Security more than two years ago, on 13 January 2014. While the authorities continue to deny his detention claiming that Ashraf left Egypt, his wife was told by several former detainees or families of detainees that he was effectively detained. She even thought she had found him when the Ministry of Interior recently listed him as serving a five-year prison sentence in Zagzagig prison, but the information was soon denied by the same Ministry, which kept on claiming they did not know anything about the victim. In last resort, Ashraf's relatives contacted Alkarama, hoping its work with the United Nations human rights protection mechanisms might help shed light on Ashraf's disappearance.

In early February 2016, the Homeland Security arrested another two young men for no apparent reason. 25-year-old real-estate agent, Abo Obida Sayed Mahmoud Abdelhameed and 28-year-old imam, Islam Ibrahim Eltohamy Ibrahim have both been missing since, and despite having solicited various official bodies, their respective families remain unaware of their fates and whereabouts. Left without any recourse at the national level, they contacted Alkarama who sent an urgent appeal to the Working Group on Enforced Disappearances (WGEID), asking this United Nations human rights mechanism to request the Egyptian authorities to immediately disclose their place of detention and authorise their families and lawyers to visit them, in accordance with Egypt's international obligations.

On 7 February 2016, teachers Medhat Mohamed Bahi Aldin Ahmed Abdelhameed and Magdy Hassan Amer Hassan disappeared following their arrest by the Egyptian police from Medhat's apartment in Giza. Despite having solicited various official bodies to establish their fates and whereabouts, their respective families, blissfully unaware of the reasons for their arrests, were met with a wall of silence. In view of the facts and the lack of remedy at the national level, and with the hope of putting an end to their enforced disappearance, Alkarama sent an urgent appeal to the Working Group on Enforced or Involuntary Disappearances (WGEID), asking this United Nations human rights protection mechanism to request the Egyptian authorities to disclose their respective places of detention and authorise their families and lawyers to visit them.

On 12 and 31 January 2016, the police respectively arrested 15-year-old Asser Mohammed Zahr Aldeen Abdelwarth and 18-year-old Abdelrahman Mohammed Saleh Mohammed at their home, in Giza and Cairo. In spite of their numerous efforts to locate them, their respective families have not heard from them since and fear that they could be tortured during their secret detention. With a view to contributing to end their ordeals, Alkarama sent an urgent appeal to the United Nations Working Group on Enforced or Involuntary Disappearances (WGEID) to ask the Egyptian authorities to disclose their places of detention and to authorise their families and lawyers to visit them immediately.